melphalan Intravenous

MEL-fa-lan

Intravenous route(Powder for Solution)

Severe bone marrow suppression with resulting infection or bleeding may occur. The IV formulation has shown more myelosuppression than oral melphalan. Hypersensitivity reactions, including anaphylaxis, have occurred in patients who received the IV formulation. Melphalan is leukemogenic in humans and produces chromosomal aberrations in vitro and in vivo and, therefore, should be considered potentially mutagenic in humans .

Commonly used brand name(s)

In the U.S.

• Alkeran IV

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Alkylating Agent

Chemical Class: Nitrogen Mustard

Uses For melphalan

Melphalan is used to treat multiple myeloma, which is a cancer in the bone marrow .

Melphalan belongs to the group of medicines called alkylating agents. It works by interfering with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by melphalan, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious, but may cause concern. Some effects may not occur for months or years after the medicine is used .

Before you begin treatment with melphalan, you and your doctor should talk about the good melphalan will do as well as the risks of using it .

melphalan is available only with your doctor's prescription .

Before Using melphalan

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For melphalan, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to melphalan or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of melphalan in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of melphalan in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment of dose in patients receiving melphalan .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving melphalan, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using melphalan with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using melphalan with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Bacillus of Calmette and Guerin Vaccine, Live


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Mumps Virus Vaccine, Live


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• Typhoid Vaccine


• Varicella Virus Vaccine


• Yellow Fever Vaccine

Using melphalan with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Buthionine Sulfoximine


• Nalidixic Acid

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of melphalan. Make sure you tell your doctor if you have any other medical problems, especially:

• Bone marrow suppression or


• Leukopenia (low white blood cells in the blood) or


• Thrombocytopenia (low platelets in the blood)—May make these conditions worse .

• Infection—May decrease your body’s ability to fight infections .

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body .

Proper Use of melphalan

You will receive melphalan while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you melphalan. melphalan is given through a needle placed in one of your veins .

Precautions While Using melphalan

It is very important that your doctor check your progress at regular visits to make sure melphalan is working properly. Blood tests may be needed to check for unwanted effects .

melphalan may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have itching; hives; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using melphalan .

Using melphalan while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. You should not breastfeed during treatment with melphalan .

If you plan to have children, talk with your doctor before using melphalan. Some men and women using melphalan have become infertile (unable to have children) .

While you are being treated with melphalan, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Melphalan may lower your body's resistance, and there is a chance you might get the infection the vaccine is meant to prevent. In addition, other persons living in your household should not receive certain vaccines, since there is a chance they could pass the infection on to you. If you have questions about this, talk to your doctor .

Melphalan can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur .

melphalan Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Chest pain


• chills


• cough or hoarseness


• fever


• lower back or side pain


• painful or difficult urination


• shortness of breath


• sores, ulcers, or white spots on the lips or in the mouth


• swollen glands


• unusual bleeding or bruising


• unusual tiredness or weakness

Incidence not known

• Abdominal or stomach pain


• absent, missed, or irregular menstrual periods


• back or leg pains


• bleeding gums


• bloated abdomen


• blurred vision


• clay-colored stools


• confusion


• dark urine


• difficult or labored breathing


• difficulty swallowing


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


• fast, pounding, or irregular heartbeat or pulse


• general body swelling


• headache


• hives


• indigestion


• itching


• light-colored stools


• loss of appetite


• nausea and vomiting


• noisy breathing


• nosebleeds


• pain and fullness in right upper abdomen


• pale skin


• puffiness or swelling of the eyelids or around the eyes, face, lips or tongue


• rash


• reddening of the skin, especially around ears swelling of eyes, face, or inside of nose


• skin rash


• sore throat


• sweating


• swelling of face, hands, ankles, feet, or lower legs


• tightness in chest


• unpleasant breath odor


• unusual lumps or masses


• vomiting of blood


• weight gain


• weight loss


• wheezing


• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Black, tarry stools


• blood in urine


• bloody stools


• change in frequency of urination or amount of urine


• coma


• convulsions


• cracked lips


• decrease in consciousness


• diarrhea


• drowsiness


• flushing of skin or feeling of warmth


• increased salivation or sweating


• increased thirst


• muscle pain or cramps


• no muscle tone or movement


• seizures


• severe nausea and vomiting


• stomach discomfort, cramps, or tenderness


• swelling or inflammation of the mouth


• troubled breathing


• vomiting of material that looks like coffee grounds


• watery or bloody diarrhea


• weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Indigestion


• passing of gas


• stomach fullness

Incidence not known

• Blue-green to black skin discoloration


• hair loss, thinning of hair


• pain, redness, soreness, or sloughing of skin at place of injection


• sores, welting, or blisters

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: melphalan Intravenous side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More melphalan Intravenous resources

• Melphalan Intravenous Side Effects (in more detail)
• Melphalan Intravenous Use in Pregnancy & Breastfeeding
• Melphalan Intravenous Drug Interactions
• Melphalan Intravenous Support Group
• 0 Reviews for Melphalan Intravenous - Add your own review/rating

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• Multiple Myeloma
• Ovarian Cancer

Sentry HC Worm X

Dosage Form: FOR ANIMAL USE ONLY
Broad Spectrum De-Wormer Chewable Tablets for Large Dogs

INDICATIONS & USAGE

For Removal of Hookworms in Puppies and Dogs

• Ancylostoma caninum


• Uncinaria stenocephala

For Removal of Large Roundworms (Ascarids) in Puppies and Dogs

• Toxocara canis


• Toxascaris leonina

To Prevent Reinfection of Large Roundworms in Puppies, Adult Dogs and Lactating Bitches After Whelping

• Toxocara canis

ACTIVE INGREDIENT (in each chewable)

Pyrantel Pamoate (113.5 mg)

How is Sentry HC Worm X Supplied

Net Contents:    2 Tablet Count

Net Contents:    4 Tablet Count

Net Contents:  12 Tablet Count

STORAGE

Store at controlled room temperature of 59-86 degrees F (15-30 degrees C).

PACKAGE LABEL PRINCIPAL DISPLAY PANEL

Sentry HC Worm X


Distributed by:


Sergeant's Pet Care Products, Inc., Omaha NE 68130


www.sentrypetcare.com


ANADA #200-281, Approved by FDA

Sentry HC Worm X  pyrantel pamoate  tablet, chewable

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 21091-402 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength PYRANTEL PAMOATE (PYRANTEL) PYRANTEL PAMOATE 113.5 mg

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color brown Score no score Shape ROUND Size 10mm Flavor LIVER (Pork Liver Powder) Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 21091-402-02 1 BLISTER PACK In 1 CARTON contains a BLISTER PACK 1 2 TABLET In 1 BLISTER PACK This package is contained within the CARTON (21091-402-02) 2 21091-402-04 2 BLISTER PACK In 1 CARTON contains a BLISTER PACK 2 4 TABLET In 1 BLISTER PACK This package is contained within the CARTON (21091-402-04) 3 21091-402-12 6 BLISTER PACK In 1 CARTON contains a BLISTER PACK 3 12 TABLET In 1 BLISTER PACK This package is contained within the CARTON (21091-402-12)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
ANADA	ANADA200281	01/16/2008

Labeler - Sergeant's Pet Care Products, Inc. (876995171)

Establishment
Name	Address	ID/FEI	Operations
Virbac Bridgeton		808558100	manufacture

Revised: 11/2010Sergeant's Pet Care Products, Inc.

Econochlor

Dosage Form: ophthalmic solution and ointment

Bone marrow hypoplasia, including aplastic anemia and death has been reported following local application of chloramphenicol. Chloramphenicol should not be used when less potentially dangerous agents would be expected to provide effective treatment.

DESCRIPTION

Econochlor® (Chloramphenicol) is a sterile topical ophthalmic antibacterial prepared in solution and ointment forms. The active ingredient is represented by the chemical structure:

Established name:

Chloramphenicol

Chemical name:

Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2- (4-nitrophenyl) ethyl]-, [R-(R*,R)]-

Each ml of solution contains: Active: Chloramphenicol 0.5% (5mg/ml). Preservative: Thimerosal 0.01%. Vehicle: Hydroxypropyl Methylcellulose: Inactive: Boric Acid, Sodium Borate (to adjust pH), Purified Water.

DM-00

Each gram of ointment contains: Active: Chloramphenicol 1.0% (10 mg/g). Inactive: Mineral Oil, Anhydrous Liquid Lanolin, White Petrolatum.

DM-00

CLINICAL PHARMACOLOGY

Chloramphenicol is a broad-spectrum antibiotic originally isolated from Streptomyces venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes. Development of resistance to chloramphenicol can be regarded as minimal for staphylococci and many other species of bacteria.

INDICATIONS USAGE

Chloramphenicol should be used only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated. Bacteriological studies should be performed to determine the causative organisms and their sensitivity to chloramphenicol (See Box Warning). For treatment of ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms.

Chloramphenicol has a wide spectrum of antimicrobial activity and is effective against many gram negative and gram positive bacteria, including the following common eye pathogens:

Staphylococcus aureus

Streptococci, including Streptococcus pneumoniae

Escherichia coli

Haemophilus influenzae

Klebsiella/Enterobacter species

Neisseria species

Moraxella lacunata (Morax-Axenfeld bacillus)

The product does not provide adequate coverage against:

Pseudomonas aeruginosa

Serratia marcescens

CONTRAINDICATIONS

This product is contraindicated in those persons who have shown hypersensitivity to any of its components.

WARNINGS

SEE BOX WARNING.

Ophthalmic ointment may retard corneal wound healing.

PRECAUTIONS

Prolonged use of antibiotics may occasionally result in overgrowth of non-susceptible organisms, including fungi. If new infections appear during treatment, the therapy should be altered. In all serious infections, the topical use of chloramphenicol should be supplemented by appropriate systemic medication.

ADVERSE REACTIONS

Blood dyscrasias may be associated with the systemic use of chloramphenicol. One case of bone-marrow hypoplasia following the prolonged (23 month) topical use of chloramphenicol ophthalmic solution has been reported.

DOSAGE ADMINISTRATION

Solution: In severe disease, instill two drops on the eye(s) hourly until improvement, following which treatment should be diminished prior to discontinuation. In mild disease, drops may be used four times daily. Ointment: Apply a small amount to the lower conjunctival sac(s) at bedtime as a supplement to the drops.

HOW SUPPLIED

Solution in 5ml (2.5ml fill) and 15ml plastic Drop-Tainer® dispensers. Ointment in 3.5 gram ophthalmic tube. Rx only.

2.5ml NDC 0065-0642-25

15ml NDC 0065-0642-15

3.5 g NDC 0065-0641-35

STORAGE

Solution: Refrigerate until dispensed. Ointment: Store between 46° and 80°F.

June, 1984

29824

Printed in USA

Alcon

Alcon Laboratories, Inc.

Fort Worth, Texas 76134 USA

Econochlor  chloramphenicol  solution

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0065-0642 Route of Administration OPHTHALMIC DEA Schedule

INGREDIENTS Name (Active Moiety) Type Strength chloramphenicol (chloramphenicol) Active 5 MILLIGRAM  In 1 MILLILITER thimerosal Inactive   hydroxypropyl methylcellulose Inactive   boric acid Inactive   sodium borate Inactive   water Inactive

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0065-0642-25 2.5 mL (MILLILITER) In 1 BOTTLE, PLASTIC None 2 0065-0642-15 15 mL (MILLILITER) In 1 BOTTLE, PLASTIC None

Econochlor  chloramphenicol  ointment

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0065-0641 Route of Administration OPHTHALMIC DEA Schedule

INGREDIENTS Name (Active Moiety) Type Strength chloramphenicol (chloramphenicol) Active 10 MILLIGRAM  In 1 GRAM mineral oil Inactive   anhydrous liquid lanolin Inactive   white petrolatum Inactive

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0065-0641-35 3.5 g (GRAM) In 1 TUBE None

Revised: 07/2006Alcon Laboratories, Inc.

More Econochlor resources

• Econochlor Drug Interactions
• Econochlor Support Group
• 0 Reviews for Econochlor - Add your own review/rating

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• Conjunctivitis, Bacterial

Ircon

Generic Name: ferrous fumarate (FER us FUE ma rate)

Brand Names: Feostat, Ferrets, Hemocyte, Ircon, Nephro-Fer

What is Ircon (ferrous fumarate)?

Ferrous fumarate is a type of iron. You normally get iron from the foods you eat. In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.

Ferrous fumarate is used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).

Ferrous fumarate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Ircon (ferrous fumarate)?

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have iron overload syndrome, hemolytic anemia (a lack of red blood cells), porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system), thalassemia (a genetic disorder of red blood cells), kidney or liver disease, if you are an alcoholic, or if you receive regular blood transfusions.

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it. An overdose of iron can be fatal, especially in a young child.

Overdose symptoms may include drowsiness, severe nausea or stomach pain, vomiting, bloody diarrhea, coughing up blood or vomit that looks like coffee grounds, shallow breathing, weak and rapid pulse, cold or clammy skin, blue lips, and seizure (convulsions).

Take ferrous fumarate on an empty stomach, at least 1 hour before or 2 hours after a meal. Avoid taking antacids or antibiotics within 2 hours before or after taking ferrous fumarate .

Ferrous fumarate is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat to make sure you get enough iron from both your diet and your medication.

What should I discuss with my healthcare provider before taking Ircon (ferrous fumarate)?

Before using this medication, tell your doctor if you are allergic to any drugs or food dyes, or if you have:

• 
  

  iron overload syndrome;

  
  


• 
  

  hemolytic anemia (a lack of red blood cells);

  
  


• 
  

  porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);

  
  


• 
  

  thalassemia (a genetic disorder of red blood cells);

  
  


• 
  

  liver or kidney disease;

  
  


• 
  

  if you are an alcoholic; or

  
  


• 
  

  if you receive regular blood transfusions.

  
  

If you have any of these conditions, you may not be able to use ferrous fumarate, or you may need a dose adjustment or special tests during treatment.

It is not known whether this medication could be harmful to an unborn baby. Tell your doctor if you become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give ferrous fumarate to a child without the advice of a doctor.

How should I take Ircon (ferrous fumarate)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Take ferrous fumarate on an empty stomach, at least 1 hour before or 2 hours after a meal. Avoid taking antacids or antibiotics within 2 hours before or after taking ferrous fumarate . Take this medication with a full glass of water. Do not crush, chew, or break a ferrous fumarate tablet. Swallow the pill whole. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Ferrous fumarate can stain your teeth, but this effect is temporary. To prevent tooth staining, mix the liquid form of ferrous fumarate with water or fruit juice (not with milk) and drink the mixture through a straw. You may also clean your teeth with baking soda once per week to treat any tooth staining.

Ferrous fumarate is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat to make sure you get enough iron from both your diet and your medication.

Store ferrous fumarate at room temperature, away from moisture and heat. Keep the liquid medicine from freezing.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine, or if a child has accidentally swallowed it. An overdose of ferrous fumarate can be fatal to a child.

Overdose symptoms may include drowsiness, severe nausea or stomach pain, vomiting, bloody diarrhea, coughing up blood or vomit that looks like coffee grounds, shallow breathing, weak and rapid pulse, cold or clammy skin, blue lips, and seizure (convulsions).

What should I avoid while taking Ircon (ferrous fumarate)?

Do not take any vitamin or mineral supplements that your doctor has not prescribed or recommended.

Avoid taking an antibiotic medicine within 2 hours before or after you take ferrous fumarate. This is especially important if you are taking an antibiotic such as ciprofloxacin (Cipro), demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), norfloxacin (Noroxin), ofloxacin (Floxin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

Certain foods can also make it harder for your body to absorb ferrous fumarate. Avoid taking this medication within 1 hour before or 2 hours after eating fish, meat, liver, and whole grain or "fortified" breads or cereals.

Avoid using antacids without your doctor's advice. Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for your body to absorb ferrous fumarate.

Ircon (ferrous fumarate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor if you have serious side effects such as:

• 
  

  bright red blood in your stools; or

  
  


• 
  

  pain in your chest or throat when swallowing a ferrous fumarate tablet.

  
  

Less serious side effects may include:

• 
  

  constipation, diarrhea;

  
  


• 
  

  nausea, vomiting, heartburn;

  
  


• 
  

  stomach pain, upset stomach;

  
  


• 
  

  black or dark-colored stools or urine; or

  
  


• 
  

  temporary staining of the teeth.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Ircon (ferrous fumarate)?

The following drugs can interact with ferrous fumarate. Tell your doctor if you use any of the following:

• 
  

  acetohydroxamic acid (Lithostat);

  
  


• 
  

  cimetidine (Tagamet);

  
  


• 
  

  deferoxamine (Desferal);

  
  


• 
  

  etidronate (Didronel);

  
  


• 
  

  dimercaprol (an injection used to treat poisoning by arsenic, lead, or mercury);

  
  


• 
  

  penicillamine (Cuprimine); or

  
  


• 
  

  pancrelipase (Cotazym, Creon, Ilozyme, Pancrease, Ultrase).

  
  

This list is not complete and there may be other drugs that can interact with ferrous fumarate. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Ircon resources

• Ircon Side Effects (in more detail)
• Ircon Use in Pregnancy & Breastfeeding
• Ircon Drug Interactions
• Ircon Support Group
• 0 Reviews for Ircon - Add your own review/rating

• Ircon MedFacts Consumer Leaflet (Wolters Kluwer)


• Ferrous Fumarate MedFacts Consumer Leaflet (Wolters Kluwer)


• Femiron Advanced Consumer (Micromedex) - Includes Dosage Information


• Feostat Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Ircon with other medications

• Anemia Associated with Chronic Renal Failure
• Iron Deficiency Anemia
• Vitamin/Mineral Supplementation and Deficiency
• Vitamin/Mineral Supplementation during Pregnancy/Lactation

Where can I get more information?

• Your pharmacist can provide more information about ferrous fumarate.

See also: Ircon side effects (in more detail)

Scabies Medications

Definition of Scabies: Scabies is a contagious skin disease caused by a very small mite.

Drugs associated with Scabies

The following drugs and medications are in some way related to, or used in the treatment of Scabies. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Learn more about Scabies

Medical Encyclopedia:

• Scabies

Harvard Health Guide:

• Symptoms and treatment for Scabies

Drug List:

Acticin-Cream

Elimite-Cream

Eurax

Lice-Bedding-Spray

Nix-Complete-Lice-Treatment-System

Nix-Cream-Rinse

Nix-Lice-Control

Rid-Home-Lice-Control-Spray-For-Surfaces

Stromectol

A-Caro-25

Generic Name: beta carotene (Oral route)

bay-ta KAR-oh-teen

Commonly used brand name(s)

In the U.S.

• A-Caro-25


• Lumitene

Available Dosage Forms:

• Capsule


• Capsule, Liquid Filled


• Liquid


• Tablet

Therapeutic Class: Nutritive Agent

Pharmacologic Class: Vitamin A (class)

Uses For A-Caro-25

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Beta-carotene is converted in the body to vitamin A, which is necessary for healthy eyes and skin.

A lack of vitamin A may cause a rare condition called night blindness (problems seeing in the dark). It may also cause dry eyes, eye infections, skin problems, and slowed growth. Your health care professional may treat these problems by prescribing either beta-carotene, which your body can change into vitamin A, or vitamin A for you.

Some conditions may increase your need for vitamin A. These include:

• Cystic fibrosis


• Diarrhea, continuing


• Illness, long-term


• Injury, serious


• Liver disease


• Malabsorption problems


• Pancreas disease

Increased need for vitamin A should be determined by your health care professional.

Claims that beta-carotene is effective as a sunscreen have not been proven. Although beta-carotene supplements are being studied for their ability to reduce the risk of certain types of cancer and possibly heart disease, there is not enough information to show that this is effective.

Beta-carotene may be used to treat other conditions as determined by your doctor.

Beta-carotene is available without a prescription.

Once a product has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, beta-carotene is used in certain patients with the following medical conditions:

• Polymorphous light eruption (a type of reaction to sun)


• Erythropoietic protoporphyria photosensitivity reaction (a type of reaction to sun)

Other than the above information, there is no additional information relating to proper use, precautions, or side effects for these uses.

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.

It is documented that people who consume diets high in fruits and vegetables have a reduced risk of heart disease and certain cancers. Fruits and vegetables are rich in beta-carotene and other nutrients that may be beneficial.

Beta-carotene is found in carrots; dark-green leafy vegetables, such as spinach and green leaf lettuce; sweet potatoes; broccoli; cantaloupe; and winter squash. The body converts beta-carotene into vitamin A. Ordinary cooking does not destroy beta-carotene.

Vitamins alone will not take the place of a good diet and will not provide energy. Your body needs other substances found in food, such as protein, minerals, carbohydrates, and fat. Vitamins themselves often cannot work without the presence of other foods. For example, some fat is needed so that beta-carotene can be absorbed into the body.

Before Using A-Caro-25

If you are taking this dietary supplement without a prescription, carefully read and follow any precautions on the label. For this supplement, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Problems in children have not been documented with intake of normal daily recommended amounts.

Geriatric

Problems in older adults have not been documented with intake of normal daily recommended amounts.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this dietary supplement. Make sure you tell your doctor if you have any other medical problems, especially:

• Eating disorders or


• Kidney disease or


• Liver disease—These conditions may cause high blood levels of beta-carotene, which may increase the chance of side effects

Proper Use of beta carotene

This section provides information on the proper use of a number of products that contain beta carotene. It may not be specific to A-Caro-25. Please read with care.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For use as a dietary supplement:

• For oral dosage forms (capsules or chewable tablets):
  
  • Adults and teenagers: 6 to 15 milligrams (mg) of beta-carotene (the equivalent of 10,000 to 25,000 Units of vitamin A activity) per day.
  
  
  • Children: 3 to 6 mg of beta-carotene (the equivalent of 5,000 to 10,000 Units of vitamin A activity) per day.
  
  

For other uses:

• For oral dosage forms (capsules or tablets):
  
  • To treat or prevent a reaction to sun in patients with erythropoietic protoporphyria:
    
    • Adults and teenagers—30 to 300 milligrams (mg) of beta-carotene (the equivalent of 50,000 to 500,000 Units of vitamin A activity) a day.
    
    
    • Children—30 to 150 mg of beta-carotene (the equivalent of 50,000 to 250,000 Units of vitamin A activity) a day.
    
    
  
  
  • To treat or prevent a reaction to sun in patients with polymorphous light eruption:
    
    • Adults and teenagers—75 to 180 mg of beta-carotene (the equivalent of 125,000 to 300,000 Units of vitamin A activity) a day.
    
    
    • Children—30 to 150 mg of beta-carotene (the equivalent of 50,000 to 250,000 Units of vitamin A activity) a day.
    
    
  
  

If you have high blood levels of vitamin A, your body will convert less beta-carotene to vitamin A.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss taking a vitamin for one or more days there is no cause for concern, since it takes some time for your body to become seriously low in vitamins. However, if your health care professional has recommended that you take this vitamin, try to remember to take it as directed every day.

If you miss a dose and you are using it as medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not refrigerate. Keep from freezing.

Store the dietary supplement in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using A-Caro-25

Use of beta-carotene has been associated with an increased risk of lung cancer in people who smoke or who have been exposed to asbestos. One study of 29,000 male smokers found an 18% increase in lung cancer in the group receiving 20 mg of beta-carotene a day for 5 to 8 years. Another study of 18,000 people found 28% more lung cancers in people with a history of smoking and/or asbestos exposure. These people took 30 mg of beta-carotene in addition to 25,000 Units of retinol (a form of vitamin A) a day for 4 years. However, one study of 22,000 male physicians, some of them smokers or former smokers, found no increase in lung cancer. These people took 50 mg of beta-carotene every other day for 12 years. If you smoke or have a history of smoking or asbestos exposure, you should not take large amounts of beta-carotene supplements for long periods of time. However, foods that are rich in beta-carotene are considered safe and appear to lower the risk of some types of cancer and possibly heart disease.

A-Caro-25 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Yellowing of palms, hands, or soles of feet, and to a lesser extent the face (this may be a sign that your dose of beta-carotene as a nutritional supplement is too high)

Rare

• Diarrhea


• dizziness


• joint pain


• unusual bleeding or bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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More A-Caro-25 resources

• A-Caro-25 Use in Pregnancy & Breastfeeding
• A-Caro-25 Drug Interactions
• A-Caro-25 Support Group
• 0 Reviews for A-Caro-25 - Add your own review/rating

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